Structure of PDB 7n61 Chain 1A Binding Site BS01

Receptor Information
>7n61 Chain 1A (length=404) Species: 3055 (Chlamydomonas reinhardtii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKVFVRTRPTATSGSGLKLGPDGQSVSVNVPKDLSAGPVNNQQEQFSFKF
DGVLENVSQEAAYTTLAHEVVDSLMAGYNGTIFAYGQTGAGKTFTMSGGG
TAYAHRGLIPRAIHHVFREVDMRADKMYRVHVSYLEIYNEQLYDLLGDTP
GTSDALAVLEDSNSNTYVRGLTLVPVRSEEEALAQFFLGEQGRTTAGHVL
NAESSRSHTVFTIHVEMRTSDAASERAVLSKLNLVDLAGSERTKKTGVTG
QTLKEAQFINRSLSFLEQTVNALSRKDTYVPFRQTKLTAVLRDALGGNCK
TVMVANIWAEPSHNEETLSTLRFASRVRALLLRRYERQIKELKAELAMRD
TLSGKGRVSYDDLTDDELRELHATCRRFLHGEAEPEDLPADSMKRVRETF
KALR
Ligand information
Ligand IDADP
InChIInChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyXTWYTFMLZFPYCI-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P@@](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N
FormulaC10 H15 N5 O10 P2
NameADENOSINE-5'-DIPHOSPHATE
ChEMBLCHEMBL14830
DrugBankDB16833
ZINCZINC000012360703
PDB chain7n61 Chain 1A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7n61 Cryo-EM structure of an active central apparatus.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R13 T93 G94 G96 K97 T98 F99 N206 S209 S210
Binding residue
(residue number reindexed from 1)		R8 T88 G89 G91 K92 T93 F94 N201 S204 S205
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0007018 microtubule-based movement
Cellular Component
GO:0005871 kinesin complex
GO:0005874 microtubule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7n61, PDBe:7n61, PDBj:7n61
PDBsum7n61
PubMed35578022
UniProtA8I9T2

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