Structure of PDB 8vtx Chain 14 Binding Site BS01
Receptor Information
>8vtx Chain 14 (length=69) Species:
300852
(Thermus thermophilus HB8) [
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MKEGIHPKLVPARIICGCGNVIETYSTKPEIYVEVCSKCHPFYTGQQRFV
DTEGRVERFQRRYGDSYRK
Ligand information
>8vtx Chain 1B (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
<<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>.>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
8vtx
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
M1 K2 H6
Binding residue
(residue number reindexed from 1)
M1 K2 H6
External links
PDB
RCSB:8vtx
,
PDBe:8vtx
,
PDBj:8vtx
PDBsum
8vtx
PubMed
39039256
UniProt
Q5SJE1
|RL31_THET8 Large ribosomal subunit protein bL31 (Gene Name=rpmE)
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