Structure of PDB 8fnc Chain 10 Binding Site BS01

Receptor Information
>8fnc Chain 10 (length=416) Species: 5691 (Trypanosoma brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLPVSYSPGSVTSTAITAHCDVLSECVAKADELAVQLKTQEGMEEFVEEL
KTSATNEMTALVKQMQTTPLLQRAGMHELRRTLYYTTSLKERDWLEEKQY
TAAMRMLTVEVLRRDGDGVLSADDVLYVTTHVVTANFYNRHLWNRMEKSL
LKFSNYENIDMSSVKAFSTRLFKTRRGCAKETLDIRRKVLLAMSRRVGVL
ANDFDLPSLLGVLQCYTVHDLTPFHLEPLAIRATNHVGDFTPHECATLAH
VLRKWRTMRLEVCERLVERICTSDQLTHHMANAAMIAIRTCFNQVSDGGR
NAMNAEPTRQKLRAMGEQIGCRLDEVEYPALPVILSILDVVVTLKIYVPK
KCLQVIFSQANDMVAIVMEQKDDPITAEEGRQLQALLSHYGNDLAPELSQ
RMKEAFREGVLPDEAS
Ligand information
Receptor-Ligand Complex Structure
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PDB8fnc Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Resolution3.3 Å
Binding residue
(original residue number in PDB)
F268 R310 H340
Binding residue
(residue number reindexed from 1)
F153 R195 H225
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000963 mitochondrial RNA processing
GO:0016554 cytidine to uridine editing
GO:0048255 mRNA stabilization
Cellular Component
GO:0005739 mitochondrion
GO:0031019 mitochondrial mRNA editing complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8fnc, PDBe:8fnc, PDBj:8fnc
PDBsum8fnc
PubMed37410820
UniProtQ57VS6

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