Structure of PDB 8fvj Chain 1 Binding Site BS01

Receptor Information
>8fvj Chain 1 (length=162) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NRWQVMIVWQVDRMRINTWKRLVKHHMYISRKAKDWFYRHHYESTHPKIS
SEVHIPLGDAKLVITTYWGLHTGLGQGVSIEWRKKRYSTQVDPDLADQLI
HLHYFDCFSESAIRNTILGRIVSPRCEYQAGHNVGSLQYLALAALIKPIK
PPLPSVRKLTED
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8fvj Chain 1 Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8fvj Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H
Resolution3.54 Å
Binding residue
(original residue number in PDB)		H108 C114 C133 H139
Binding residue
(residue number reindexed from 1)		H101 C107 C126 H132
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0019058 viral life cycle
Cellular Component
GO:0016020 membrane
GO:0020002 host cell plasma membrane
GO:0030430 host cell cytoplasm
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fvj, PDBe:8fvj, PDBj:8fvj
PDBsum8fvj
PubMed37640699
UniProtP12504|VIF_HV1N5 Virion infectivity factor (Gene Name=vif)

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