Structure of PDB 7nhk Chain 1 Binding Site BS01

Receptor Information
>7nhk Chain 1 (length=59) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVKEIRELTTAEMLDKEKQLKEELFNLRFQLATGQLENTARIKEVRQSIA
RIKTVLREQ
Ligand information
>7nhk Chain A (length=2905) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaagugaauaagggcgcacgguggaugccuuggcacuaggagccgauga
aggacgggacuaacaccgauaugcuuuggggagcuguaaguaagcuauga
uccagagauuuccgaaugggggaacccaauaucuuuuauaggauauuacu
uuucagugaauacauagcugauuagagguagacgcagagaacugaaacau
cuuaguaccugcaggaagagaaagaaaauucgauucccugaguagcggcg
agcgaaacgggaagagcccaaaccaacaagcuuguugggguuguaggacu
ccgauaugguagucuguuaguauaguugaaggauuuggaaaauuccgcua
aagagggugaaagccccguagacgaaaugcugacaacaccuaggaggauc
cugaguacggcggaacacgagaaauuccgucggaauccgcggggaccauc
ccgcaaggcuaaauacucccuagugaccgauagugaaccaguaccgugag
ggaaaggugaaaagcaccccggaaggggagugaaauagauccugaaaccg
ugugccuacaacaagucaaagcucguuaaugagugauggcgugccuuuug
uagaaugaaccggcgaguuacgauugcaugcgagguuaagucgaagagac
ggagccgcagcgaaagcgagucugaauagggcgaaugaguauguagucgu
agacccgaaaccaugugaucuacccauguccagguugaaggugcgguaaa
acgcacuggaggaccgaacccacguacguugaaaagugcggggaugaggu
guggguagcggagaaauuccaaacgaacuuggagauagcugguucucucc
gaaauagcuuuagggcuagccucggaauugagaaugauggagguagagca
cuguuuggacuaggggcccaucucggguuaccgaauucagauaaacuccg
aaugccauucauuuauauccgggagucagacugcgagugauaagauccgu
agucgaaagggaaacagcccagaccaccagcuaaggucccaaaauauaug
uuaaguggaaaaggaugugggguugcacagacaacuaggauguuggcuua
gaagcagccaccauuuaaagagugcguaauagcucacuagucgagugacc
cugcgccgaaaauguaccggggcuaaacauauuaccgaagcuguggacua
caccauuagguguagugguaggagagcguucuaagggcguugaaggucga
ucgugaggacggcuggagcgcuuagaagugagaaugccgguaugaguagc
gaaagacaggugagaauccuguccaccguaugacuaagguuuccugggga
aggcucguccgcccaggguuagucgggaccuaagccgaggccgauaggcg
uaggcgauggacaacagguugauauuccuguaccaguuguuuuuguuuga
gcaauggagggacgcaguaggcuaaggaaugcaugcgauuggaagugcau
guccaagcaaugagucuugaguagaguuaaaugcuuuacucuuuaaggac
aaguugugacggggagcgaaauaauaguagcgaaguuccugacgucacac
ugccaagaaaagcuucuagugagaaaacaacugcccguaccguaaaccga
cacagguagucgaggagaguauccuaaggugagcgagcgaacucucguua
aggaacucggcaaaaugaccccguaacuucgggagaaggggugcugacuu
cggucagccgcagugaauaggcccaagcgacuguuuaucaaaaacacagg
ucucugcaaaaucguaagaugaaguauaggggcugacgccugcccggugc
uggaagguuaagaggauggguuagcuucggcgaagcucagaauugaagcc
ccaguaaacggcggccguaacuauaacgguccuaagguagcgaaauuccu
ugucggguaaguuccgacccgcacgaaaggcguaacgauuugggcacugu
cucaacgagagacucggugaaauuuuaguaccugugaagaugcagguuac
ccgcgacaggacggaaagaccccauggagcuuuacuguaguuugauauug
aguguuuguaccacauguacaggauagguaggagccgaugagaccggaac
gcuaguuucggaggaggcgcuggugggauacuacccuuguguuaugaacc
cucuaacccgcaccacuaaucguggugggagacagugucagaugggcagu
uugacuggggcggucgccuccuaaaagguaacggaggcgcccaaagguuc
ccucagaaugguuggaaaucauucgaagaguguaaaggcagaagggagcu
ugacugcgagaccuacaagucgagcagggacgaaagucgggcuuagugau
ccggugguuccgcauggaagggccaucgcucaacggauaaaagcuacccu
ggggauaacaggcuuaucucccccaagaguccacaucgacggggagguuu
ggcaccucgaugucggcucgucgcauccuggggcuguagucggucccaag
gguugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgu
cgugagacaguucggucccuauccgucgcgggcguuggaaauuugagagg
agcuguccuuaguacgagaggaccgggauggacuuaccgcugguguacca
guuguucugccaagggcauugcuggguagcuauguagggaagggauaaac
gcugaaagcaucuaagugugaagcccaccucaagaugagauuucccauuu
cuuuaagaaaguaagaccccugagagaugaucagguagauagguuggaag
uggaaggcuagugauaguuggagcggaccaauacuaaucggucgaggacu
uaacc
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....<<<.....))>>>...>>>...>>>>>>>>>>>>>>..>>>>..>>
>>.....<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>
>>>>..)))......]].>>>>>>>.]]...............<<....>
>....]].........<<<<....>>>>..................>>>>
>>>>>>>.......<<<<..<<<<......>>>>..>>>>...<.<....
....>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<<<.....>>>
...>>>...<<....>>..<<<<.....>>>>......>>>>>>>>>>>>
>..<<.<...<<<.<<.....<<<<<<<<<..<<<....<<<<<<.....
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....>>>>.>>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>
>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<
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....>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.
<<...............<<<<<...............>>>>><<<<<<..
..>>>>>>............<<<<<<<<<..<<<.........>>>..<<
<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<
<<<..<<<...<<...<<<<<..<<....>>...>>>>>...>>...>>>
>>>>>..>>>>><<<<<<.......>>>>>>........<..........
.<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>.....
>>.>>>>>>>>.>>>>>>...........<<<<<........>>>>>..<
<<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<
<<.<<<<<<<.<<<<...........<<<<<..<<<.......<<<<<<<
....>>>>>>>....>>>............>>>>>..>>>>.>>>>>>>.
>>>....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>
..<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<
<<...<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>
...<<<<..<<<......>>>..>>>>.<<<....>>>.>>)))].....
.<<<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>
>>>.......<<<<...<<<<<<...<<.......>>...>>>>>>....
>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..
>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<
<....>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<
..<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<
<<<<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<
<<<...........>>>>>...>>>>.>>>>.......>>>>>>>..<<<
<.....>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<
<.....<<<<....>>>>....>>...>>>>>.>>>...>>>>....>>>
>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7nhk Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
R7 E38 N39 T40 K44 R47 Q48 A51 R52 K54 T55 R58
Binding residue
(residue number reindexed from 1)
R6 E37 N38 T39 K43 R46 Q47 A50 R51 K53 T54 R57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7nhk, PDBe:7nhk, PDBj:7nhk
PDBsum7nhk
PubMed34117249
UniProtA0A1B4XKV0

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