Structure of PDB 6mti Chain 1 Binding Site BS01

Receptor Information
>6mti Chain 1 (length=127) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKK
KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDII
GEFKVPMNTVDFGHVTEEWRDLQSAEK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6mti Chain 1 Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6mti Structural basis for the clamping and Ca2+activation of SNARE-mediated fusion by synaptotagmin.
Resolution10.4 Å
Binding residue
(original residue number in PDB)		D172 D178 F231 D232
Binding residue
(residue number reindexed from 1)		D32 D38 F91 D92
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6mti, PDBe:6mti, PDBj:6mti
PDBsum6mti
PubMed31160571
UniProtP21707|SYT1_RAT Synaptotagmin-1 (Gene Name=Syt1)

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