Structure of PDB 6c26 Chain 1 Binding Site BS01

Receptor Information
>6c26 Chain 1 (length=432) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPPATWENVDYKRTIDVSNAYISETIEITIKNIEYFTAFESGIFSKVSFF
SAYFTNEATFLNSQLLEIRYGIIQFPNAISPQEEVSLVIKSFYNTVGIPY
PEHVGMSEEQHLLWETNRLPLSAYDTKKASFTLIGSSSFEEYHPPNDESL
LGKANGNSFEFGPWEDIPRFSSNETLAIVYSHNAPLNQVVNLRRDIWLSH
WASTIQFEEYYELTNKAAKLSKGFSRLELMKQIQTQNMRQTHFVTVLDML
LPEGATDHYFTDLVGLVSTSHAERDHFFIRPRFPIFGGWNYNFTVGWTNK
LSDFLHVSSGSDEKFVASIPILNGPPDTVYDNVELSVFLPEGAEIFDIDS
PVPFTNVSIETQKSYFDLNKGHVKLTFSYRNLISQVANGQVLIKYDYPKS
SFFKKPLSIACYIFTALMGVFVLKTLNMNVTN
Ligand information
Ligand IDEGY
InChIInChI=1S/C33H66NO8P/c1-6-8-10-12-14-16-17-18-20-22-24-26-33(36)42-31(30-41-43(37,38)40-28-27-34(3,4)5)29-39-32(35)25-23-21-19-15-13-11-9-7-2/h31H,6-30H2,1-5H3/p+1/t31-/m1/s1
InChIKeyGGHWXDCJHDYMKO-WJOKGBTCSA-O
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.6CCCCCCCCCCCCCC(=O)OC(COC(=O)CCCCCCCCCC)COP(=O)(O)OCC[N+](C)(C)C
OpenEye OEToolkits 2.0.6CCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CCCCCCCCCC)COP(=O)(O)OCC[N+](C)(C)C
CACTVS 3.385CCCCCCCCCCCCCC(=O)O[CH](COC(=O)CCCCCCCCCC)CO[P](O)(=O)OCC[N+](C)(C)C
CACTVS 3.385CCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CCCCCCCCCC)CO[P](O)(=O)OCC[N+](C)(C)C
ACDLabs 12.01OP(=O)(OCC[N+](C)(C)C)OCC(COC(=O)CCCCCCCCCC)OC(=O)CCCCCCCCCCCCC
FormulaC33 H67 N O8 P
Name(4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium
ChEMBL
DrugBank
ZINC
PDB chain6c26 Chain 1 Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6c26 The atomic structure of a eukaryotic oligosaccharyltransferase complex.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		W241 Q250 E252 Y409
Binding residue
(residue number reindexed from 1)		W197 Q206 E208 Y365
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.99.18: dolichyl-diphosphooligosaccharide--protein glycotransferase.
Gene Ontology
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0016020 membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6c26, PDBe:6c26, PDBj:6c26
PDBsum6c26
PubMed29466327
UniProtP41543|OST1_YEAST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Gene Name=OST1)

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