Structure of PDB 1tme Chain 1 Binding Site BS01

Receptor Information
>1tme Chain 1 (length=256) Species: 12126 (Theiler's encephalomyelitis virus (STRAIN DA)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSDNAEKGKVSNDDASVDFVAEPVKLPENQTRVAFFYDRAVPIGMLRPGQ
NIESTFVYQENDLRLNCLLLTPLPSFCPDSTSGPVKTKAPVQWRWVRSGG
TTNFPLMTKQDYAFLCFSPFTYYKCDLEVTVSALGTDTVASVLRWAPTGA
PADVTDQLIGYTPSLGETRNPHMWLVGAGNTQISFVVPYNSPLSVLPAAW
FNGWSDFGNTKDFGVAPNADFGRLWIQGNTSASVRIRYKKMKVFCPRPTL
FFPWPV
Ligand information
>1tme Chain 4 (length=25) Species: 12126 (Theiler's encephalomyelitis virus (STRAIN DA)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SGNEGVIINNFYSNQYQNSIDLSAS
Receptor-Ligand Complex Structure
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PDB1tme Three-dimensional structure of Theiler virus.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
F35 D38 D126 R237 K239 K240
Binding residue
(residue number reindexed from 1)
F35 D38 D126 R237 K239 K240
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.6.4.13: RNA helicase.
External links
PDB RCSB:1tme, PDBe:1tme, PDBj:1tme
PDBsum1tme
PubMed1549565
UniProtP13899|POLG_TMEVD Genome polyprotein

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