Structure of PDB 1r1a Chain 1 Binding Site BS01

Receptor Information
>1r1a Chain 1 (length=283) Species: 12134 (Human rhinovirus 1A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NYIDEVLNEVLVVPNIKESHHTTSNSAPLLDAAETGHTSNVQPEDAIETR
YVITSQTRDEMSIESFLGRSGCVHISRIKVDYTDYNGQDINFTKWKITLQ
EMAQIRRKFELFTYVRFDSEITLVPCIAGRGDDIGHIVMQYMYVPPGAPI
PSKRNDFSWQSGTNMSIFWQHGQPFPRFSIPFLSIASAYYMFYDGYDGDN
TSSKYGSVVTNDMGTICSRIVTEKQKLSVVITTHIYHKAKHTKAWCPRPP
RAVPYTHSHVTNYMPETGDVTTAIVRRNTITTA
Ligand information
>1r1a Chain 4 (length=19) Species: 12134 (Human rhinovirus 1A) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
YFNINYFKDAASSGASRLD
Receptor-Ligand Complex Structure
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PDB1r1a Crystal structure of human rhinovirus serotype 1A (HRV1A).
Resolution3.2 Å
Binding residue
(original residue number in PDB)		N5 E9 V14 L15 D63 E68 D122 S183 P185 K244 H245
Binding residue
(residue number reindexed from 1)		N1 E5 V10 L11 D59 E64 D118 S179 P181 K240 H241
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1r1a, PDBe:1r1a, PDBj:1r1a
PDBsum1r1a
PubMed2555523
UniProtP23008|POLG_HRV1A Genome polyprotein

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