Structure of PDB 1qgc Chain 1 Binding Site BS01

Receptor Information
>1qgc Chain 1 (length=183) Species: 12116 (Foot and mouth disease virus C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTTTGESADPVTTTVENYGGETQVQRRHHTDVAFVLDRFVKVTVSDNQHT
LDVMQAHKDNIVGALLRAATYYFSDLEIAVTHTGKLTWVPNGAPVSALNN
TTNPTAYHKGPVTRLALPYTAPHRVLATAYTGTSFNFGAVKAETITELLV
RMKRAELYCPRPILPIQPTGDRHKQPLVAPAKQ
Ligand information
>1qgc Chain 5 (length=24) Species: 12116 (Foot and mouth disease virus C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TTAYTASARGDLAHLTTTAARTLP
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1qgc Structure of the complex of an Fab fragment of a neutralizing antibody with foot-and-mouth disease virus: positioning of a highly mobile antigenic loop.
Resolution30.0 Å
Binding residue
(original residue number in PDB)		A127 Y130 G132 T161 S162 F163
Binding residue
(residue number reindexed from 1)		A127 Y130 G132 T133 S134 F135
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.46: L-peptidase.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:1qgc, PDBe:1qgc, PDBj:1qgc
PDBsum1qgc
PubMed9130694
UniProtP03311|POLG_FMDVS Genome polyprotein

[Back to BioLiP]