Structure of PDB 1fpn Chain 1 Binding Site BS01

Receptor Information
>1fpn Chain 1 (length=269) Species: 12130 (rhinovirus A2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LVVPNINSSNPTTSNSAPALDAAETGHTSSVQPEDVIETRYVQTSQTRDE
MSLESFLGRSGCIHESKLEVTLANYNKENFTVWAINLQEMAQIRRKFELF
TYTRFDSEITLVPCISALSQDIGHITMQYMYVPPGAPVPNSRDDYAWQSG
TNASVFWQHGQAYPRFSLPFLSVASAYYMFYDGYDEQDQNYGTANTNNMG
SLCSRIVTEKHIHKVHIMTRIYHKAKHVKAWCPRPPRALEYTRAHRTNFK
IEDRSIQTAIVTRPIITTA
Ligand information
>1fpn Chain 4 (length=25) Species: 12130 (rhinovirus A2) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AQVSRQNYFNINYFKDAASNGASKL
Receptor-Ligand Complex Structure
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PDB1fpn Structure of human rhinovirus serotype 2 (HRV2).
Resolution2.6 Å
Binding residue
(original residue number in PDB)		D63 S66 E68 D120 S181 P183 K240 H241
Binding residue
(residue number reindexed from 1)		D49 S52 E54 D106 S167 P169 K226 H227
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1fpn, PDBe:1fpn, PDBj:1fpn
PDBsum1fpn
PubMed10903863
UniProtP04936|POLG_HRV2 Genome polyprotein

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