Structure of PDB 1bev Chain 1 Binding Site BS01

Receptor Information
>1bev Chain 1 (length=268) Species: 12065 (Bovine enterovirus strain VG-5-27) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QAAGALVAGTSTSTHSVATDSTPALQAAETGATSTARDESMIETRTIVPT
HGIHETSVESFFGRSSLVGMPLLATGTSITHWRIDFREFVQLRAKMSWFT
YMRFDVEFTIIATSSTGQNVTTEQHTTYQVMYVPPGAPVPSNQDSFQWQS
GCNPSVFADTDGPPAQFSVPFMSSANAYSTVYDGYARFMDTDPDRYGILP
SNFLGFMYFRTLEDAAHQVRFRIYAKIKHTSCWIPRAPRQAPYKKRYNLV
FSGDSDRICSNRASLTSY
Ligand information
Ligand IDMYR
InChIInChI=1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16)
InChIKeyTUNFSRHWOTWDNC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385CCCCCCCCCCCCCC(O)=O
OpenEye OEToolkits 1.7.6CCCCCCCCCCCCCC(=O)O
ACDLabs 12.01O=C(O)CCCCCCCCCCCCC
FormulaC14 H28 O2
NameMYRISTIC ACID
ChEMBLCHEMBL111077
DrugBankDB08231
ZINCZINC000001530417
PDB chain1bev Chain 1 Residue 900 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1bev Implications for viral uncoating from the structure of bovine enterovirus.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		D98 Y145 Y191
Binding residue
(residue number reindexed from 1)		D85 Y132 Y178
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
External links
PDB RCSB:1bev, PDBe:1bev, PDBj:1bev
PDBsum1bev
PubMed7773791
UniProtP12915|POLG_BOVEV Genome polyprotein

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