Structure of PDB 8d8k Chain 0 Binding Site BS01

Receptor Information
>8d8k Chain 0 (length=429) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELRLLSKTLQGQSYRDQLELNPDVSKAINNNIMAVHIPNNLRRVATNYYK
EIQEPNSLHRPCRTKMEVDAHIASIFLQNYGSIFQSLKELQKRVGPDNFK
PQRILDVGYGPATGIVALNDILGPNYRPDLKDAVILGNAEMQERAKIILS
RQLIMTNLRSSIPASKEYDLIILTHQLLHDGNQFPIQVDENIEHYLNILA
PGGHIVIIERGNPMGFEIIARARQITLRPENFPDEFGKIPRPWNYFLKVI
APCPHQRKCPLQVGNPNFYTHKEGKDLKFCNFQKSIKRPKFSIELKKGKL
LATSWDNGRDYEILNYSYLIFERSHKDENTLKEIKKLRNENVNGKYDIGS
LGDDTQNSWPRIINDPVKRKGHVMMDLCAPSGELEKWTVSRSFSKQIYHD
ARKSKKGDLWASAAKTQIKGLGDLNVKKF
Ligand information
>8d8k Chain a (length=1538) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuuuauauauauauaauaaggaaaaguauuuauaagaauaugauguuggu
ucagauuaagcgcuaaauaaggacaugacacaugcgaaucauacguuuau
uauugagauaauaaauaugugguguaaacgugaguaauuuuauuaggaau
uaaugaacuauagaauaagcuaaauacuuaauauuauauaaaaauaauuu
auauaauaaaaaggauauauauauauauauuuaucuauagucaagccaau
aaugguuuagguaguagguuuauuaagaguuaaaccuagccaacgaucca
uaaucgauaaugaaaguuagaacgaucacguugacucugaaauauaguca
auaucuauaagauacagcagugaggaauauuggacaaugaucgaaagauu
gauccaguuacuuauuaggaugauauauauauauauauaaauugauuaaa
aauaaaauccauaaauaauuaaaauaaugauauuaauuaccauauauuua
uauggauauauauauauuuuaauaguccugacuaauauuugugccagcag
ucgcgguaacacaaagagggcgagcguuaaucauaaugguuuaaaggauc
cguagaaugaauuauauauaauuuagaguuaauaaaauauaauuaaagaa
uuauaauaguaaagaugaaauaauaauaauaauuauaagacuaauauaug
ugaaaauauuaauuaaauauuaacugacauugagggauuaaaacuagagu
agcgaaacggauucgauacccguguaguucuaguaguaaacuaugaauac
aauuauuuauaauauauauauaaauaauaaaugaaaaugaaaguauucca
ccugaagaguacguuagcaauaaugaaacucaaaacaauagacgguuaca
gacuuaagcaguggagcauguuauuuaauucgauaauccacgacuaaccu
uaccauauuuugaauauuauaauaauuauaauuauuauauuacaggcguu
acauuguugucuuuaguucgugcugcaaaguuuuagauuaaguucauaaa
cgaacaaaacuccauauauauaauuuuaauuauauauaauuuuauauuau
uuauuaauauaaagaaaggaauuaagacaaaucauaaugauccuuauaau
auggguaauagacgugcuauaauaaaaugauaauaaaauuauauaaaaua
uauuuaauuauauuuaauuaauaauauaaaacauuuuaauuuuuaauaua
uuuuuuuauuauaauaugaauuauaaucugaaauucgauuauaugaaaaa
agaauugcuaguaauacguaaauuaguauguuacggugaauauucuaacu
guuucgcacuaaucacucaucacgcguugaaacauauuauuaucuuauua
uuuauauaauauuuuuuaauaaauauuauuaauuuauauuuauuuauauc
agaaauaauaugaauuaaugcgaaguugaaauacaguuaccguaggggaa
ccugcggugggcuuauaaauaucuuaaauauucuuaca
..<<<<<<..>>>>>>...................<<<<..[.((((.>>
>>.<<<<.<<<<<..<<<<<<<<.....<<<.<<<..<<<..<<<<<<<<
<<<<..>>>>>>>>>>..>>>>>.....<<<........<<<<<.<<...
...<..<<<<<<<<.<<<<.......>>>>...<<<<<<<<<.....>>>
>>>>>>......<<<<<<<<<..>>>>>>>>>.>>>>>>>>.>..>>>>>
>><<<....<<<..<<<<<<<<........>>>>>>>>>>>......>>>
..<<<<.<<<<....>>>>...>>>>.>>><<<<<<.........>>>>>
><<<<.....>>>>..>>>>>>.........<<<....<<<<....>>>>
..>>>..>>.>>>>>>.<<<<..<<<<<<....>>>>>>..<<......>
>.....>>>>..<<<<<<<<..............>>>>><<<<<<<..>>
>>>>>.<<<<..>>>>.>>>....<<<<<(((.....<<<<.....<<.)
))>>.......>>>>.>>>>>..>>>>>>>>>.....<<<((.....<<<
<...<.<<.<<<<<<..>>>>>>...<<<<<<<<.....<<<<<<<<<..
<<<<<<<....<...........>.......>>>>>>>..>>.......<
<....>>.>>>>>>>..>>>>>>>>...>>>...>>>>....<<<<<<..
.<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<
.<<<<<<<<<<<<..>>.>>>>>>>>>>..<<..))>>....>>>>>>.>
>>.<<.......<<<<....>>>>.....>>..)))).]<<.<<...<<<
<......<<<<<..<<<<<<<<<<..........................
..<<<<<<<.....<<.<<<<<<<<<<..>>>>>>>>>>.>>.<<<.<<.
.<<<<<<<<<<<<..<<<<<<<<<....>>>....<<......>>....>
>>>>>.....<<<.<<<<<<<<........>>>>>>>>..<<<<<<<<<.
....>>>>>>>>>....>>>...>>>>>>>....>>>>>>>>>>...>>>
>>>>...>>.>>>>>>>>.....<<<<<<........<<<..<<..<<<<
<<......>>>>>>..>>....>>>......>>>>>>......<<<<<..
......>>>>>.....<....<<<<<<<........>>>>>>>....>..
...>>>>>.....<<.<<<<<.........>>>>>>>...........>>
>>..>>..>>....<.<<<.<.<<<<<<<<..<<<<<<<<<.<<<...<<
<..<<<.<<<<<...<<<<<<<...>>>>>>>...>>>>>>>>..>>>..
>>>>>>>>>>>>..>>>>>>>>..>.>>.>.>.....<<<<<<<<<....
>>>>>>>>>.............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d8k Principles of mitoribosomal small subunit assembly in eukaryotes.
Resolution3.13 Å
Binding residue
(original residue number in PDB)		H119 R123 I135 Q138 D281 Q284 I287 R311 P314 N387 K392 K398 R408 K416 K417 L421 T423 S424 W425 N442 G443 R444 D445 Y446 N450 N499 D500 R504 K505 H507 D511 K521 R537
Binding residue
(residue number reindexed from 1)		H59 R63 I75 Q78 D180 Q183 I186 R210 P213 N267 K272 K278 R288 K296 K297 L301 T303 S304 W305 N307 G308 R309 D310 Y311 N315 N364 D365 R369 K370 H372 D376 K386 R402
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008168 methyltransferase activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
GO:0180026 mitochondrial small ribosomal subunit assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8d8k, PDBe:8d8k, PDBj:8d8k
PDBsum8d8k
PubMed36482135
UniProtP36056|RT22_YEAST Ribosome assembly protein RSM22, mitochondrial (Gene Name=RSM22)

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