Structure of PDB 7ope Chain 0 Binding Site BS01

Receptor Information
>7ope Chain 0 (length=532) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFDGMFTYGMTHELNEKIMGGRITKIHQPYKHDVIFHIRAKGKNQKLLLS
AHPSYSRVHITAQAYENPSEPPMFCMLLRKHIEGGFIEKIEQAGLAAIMI
FHIKSRNEIGDETVRKLYVEIMGRHSNIILTDAAENVIIDGLKHLSPSMN
SYRTVLPGQDYKLPPAQDKISPDDILRHLSFQEGRLDKQIVDHFSGVSPL
FAKEAVHRATLPKALLALFAEVKEHRFIPNITTVNGKEYFYLLELTHLKG
EARRFDSLSELLDRFAERDRVKQQAQDLERFVVNERKKNANKIKKLEKTL
EYSENAKEFQLYGELLTANLYMLKKGDKQAEVINYESPTITIPLNPNKTP
SENAQAYFTKYQKAKNSVAVVEEQIRLAQEEIEYFDQLIQQLSSASPRDI
SEIREELVEGKYLRPHNPVLETYESTSGLTILVGKNNRQNEYLTTRVAAR
DDIWLHTKDIPGSHVVIRSSEPDEQTIMEAATIAAYFSKAKDSSSVPVDY
TKIRHVKKPKPGFVTYDSQHTVFVTPDADTVI
Ligand information
>7ope Chain A (length=2814) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaug
aaggacgggacgaacaccgauaugcuucggggagcuguaagcaagcuuug
auccggagauuuccgaauggggaaacccaccacucguaauggagugguau
ccauaucugaauucauaggauaugagaaggcagacccggggaacugaaac
aucuaaguacccggaggaagagaaagcaaaugcgauucccugaguagcgg
cgagcgaaacgggaucagcccaaaccaagaggcuugccucuugggguugu
aggacacucuguacggaguuacaaaggaacgagguagaugaagaggucug
gaaaggcccgccauaggagguaacagcccuguagucaaaacuucguucuc
uccugaguggauccugaguacggcggaacacgugaaauuccgucggaauc
cgggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaa
ccaguaccgugagggaaaggugaaaagcaccccggaaggggagugaaaga
gauccugaaaccgugugccuacaaguagucagagcccguuaacgggugau
ggcgugccuuuuguagaaugaaccggcgaguuacgaucucgugcaagguu
aagcagaagaugcggagccgcagcgaaagcgagucugaauagggcgcaug
aguacguggucguagacccgaaaccaggugaucuacccauguccagggug
aaguucagguaacacugaauggaggcccgaacccacgcacguugaaaagu
gcggggaugagguguggguaggggugaaaugccaaucgaaccuggagaua
gcugguucucuccgaaauagcuuuagggcuagccucaagguaagagucuu
ggagguagagcacugauuggacuaggggcccggguuaccgaauucaguca
aacuccgaaugccaaugacuuauccuugggagucagacugcgagugauaa
gauccguagucgaaagggaaacagcccagaccgccagcuaaggucccaaa
guauacguuaaguggaaaaggauguggaguugcuuagacaaccaggaugu
uggcuuagaagcagccaccauuuaaagagugcguaauagcucacuggucg
agugacucugcgccgaaaauguaccggggcuaaacguaucaccgaagcug
cggacuguucgaacagugguaggagagcguucuaagggcugugaagccag
accggaaggacugguggagcgcuuagaagugagaaugccgguaugaguag
cgaaagaggggugagaauccccuccaccgaaugccuaagguuuccugagg
aaggcucguccgcucaggguuagucgggaccuaagccgaggccgaaaggc
guaggcgauggacaacagguugauauuccuguaccaccuccucaccauuu
gagcaauggggggacgcaggaggauaggguaagcgcgguauuggauaucc
gcguccaagcaguuaggcugggaaauaggcaaauccguuucccaaaggcu
gagcugugauggcgagcgcgaaguuccugauuccacacugccaagaaaag
ccucuagcgaggugagaggugcccguaccgcaaaccgacacagguaggcg
aggagagaauccuaaggugaucgagagaacucucguuaaggaacucggca
aaaugaccccguaacuucgggagaaggggugcucuguuagggugcaagcc
cgagagagccgcagugaauaggcccaggcgacuguuuagcaaaaacacag
gucucugcgaagccguaaggcgaaguauaggggcugacgccugcccggug
cuggaagguuaagaggagcgcuuagcguaagcgaaggugcgaauugaagc
cccaguaaacggcggccguaacgguccuaagguagcgaaauuccuugucg
gguaaguuccgacccgcacgaaaggcgcaacgaucugggcacugucucaa
cgagagacucggugaaauuauaguaccugugaagaugcagguuacccgcg
acaggacggaaagaccccguggagcuuuacugcagccugauauugaaugu
ugguuugaccuucuaacccgccgcccuuaucgggcggggagacaguguca
ggugggcaguuugacuggggcggucgccuccuaaaagguaacggaggcgc
ccaaagguucccucagaaugguuggaaaucauucgcagaguguaaaggca
caagggagcuugacugcgagaccuacaagucgagcagggacgaaagucgg
gcuuagugauccggugguuccgcauggaagggccaucgcucaacggauaa
aagcuaccccggggauaacaggcuuaucucccccaagaguccacaucgac
ggggagguuuggcaccucgaugucggcucaucgcauccuggggcuguagu
cggucccaaggguugggcuguucgcccauuaaagcgguacgcgagcuggg
uucagaacgucgugagacaguucggucccuauccgucgcgggcgcaggaa
auuugagaggagcuguccuuaguacgagaggaccgggauggacgcaccgc
ugguguaccaguuguucugccaagggcaucgcuggguagcuaugugcgga
cgggauaagugcugaaagcaucuaagcaugaagccccccucaagaugaga
uuucccauuccgcaaggaaguaagaucccugaaagaugaucagguugaua
ggucugagguggaaguguggcgacacauggagcugacagauacuaaucga
ucgaggacuuaacc
<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<....
..<<<<<<..[..((.>>>.....<<<<<<<..<<<))..]..>>>....
.>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<
<<<<<<<<.........>>>>>>>.>>.>>....<<<<<<.....<<...
.>>......>>>>>.>.........<<....>>...<<<<......<<..
...>>.....>>>>...(((....<<<<<<<<....>>>>>>>>......
<<<<<<<<<.....<<<<.......<<<<<<<<<<.<<<.....<<<<..
....>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>>>
>>>.>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>.....
.<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]].........
......<<....>>....]].........<<<<....>>>>.........
....}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>
>>>...<.<........>.>.<<<<<<....<<<<<<<.<<<<<..<<<.
..<<<.....>>>...>>>...<<....>>..<<<<.....>>>>.....
.>>>>>.>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<..
..<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>
>>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>.
.>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<<...<<<<<<<
<<.....<<<...<<<<<<<<...<<<<<<..>>>>.>>...>>>>>>>>
..>>.>.....>>>>.>>>>>..>>>>>>>.>>..<<<<<<<.<<.....
.>>.>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((...
..<<<<<<...........<<..<<<<<<<<<........<<<<<.<<..
.<<<<.......>>>>...>>.........<<......>>...>>>>>..
..>>>>>>>>>.>>...........))).....>>>>>>.>>>...>>>>
>>><<<<<<..>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<
.<<....>>.>>>>>...>>.>>>>>>>..>.....>>>>>><......<
<....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<.
..<<.....>>.>>>>>>....((<<<<.<<.<.<<<...<<<....>>>
...>>>..>>>...<<<<<........>>>>>))<<<<..<<<<<<....
..<<...<<<<....<<<<..<<<..<<<.<<<<<<<<...(((....>>
>>>><<..<<<<<..<<<<<<<<<<<.<<.....>>>>>>>>>...>>>>
..>>>>>...>><..<..>...>>>>>>...>>>...>>>>.........
>>>>..>>..>>>>>>.>>>>>>>>..>>.....<<......>>>>>>>.
<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<.........<
.....<<<<<....<....>.....>>>>><<<<<....<<<<....>>>
>...>>>>>............<<<<<<<<<..<<<.........>>>..<
<<<<<<.....<<<....>>>.......>>>>>>>..<<<<.<<<..<<<
<<<<..<<<<..<<...<<<<<<.<<....>>..>>>>>>...>>..>>>
>>>>>>..>>>>><<<<<...>>>>>........<...........<<<<
<<.....>>>>>>.....>....>>>>...>>.>>>>>>>..>..>>.>>
>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<
<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<.<<
<<...>>>>.>>>....<<.<<<<<<.....>>>>>>>>.....>>>>>>
>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..
<<...<<<<<<<...<<<<<<.......>>>>>>.....<<.[.(((>>.
...>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>>.>
>)))]......<<<<<<<.((..>>>>..))>>>>>>>............
.>>>>..]]>>>>.......<<<<...<<<<<<...<<.......>>...
>>>>>>....>>>.>.......<<<<<.<<<<<<..<<<<<<<<<.....
.>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>
....<<<<<<<....>>>.>>>>....]]..)))>>>>>>>>....<<<<
<<<...<<<<..<<<<<<<...............>>>>>>>.<<<<<...
<<<<...<<<<<<<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>..
.<<<....<<<<<...........>>>>>....>>>.>>>>.......>>
>>>>>..<<<<....>>>>....<<<<<<<<<.......>>>>>....<<
<<<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>
>>....>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ope RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Q326 E330 T333 L336 K341 P365 S370 Q374 F377 K384
Binding residue
(residue number reindexed from 1)		Q310 E314 T317 L320 K325 P346 S351 Q355 F358 K365
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0043023 ribosomal large subunit binding
Biological Process
GO:0006412 translation
GO:0072344 rescue of stalled ribosome
Cellular Component
GO:1990112 RQC complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ope, PDBe:7ope, PDBj:7ope
PDBsum7ope
PubMed34255840
UniProtO34693|RQCH_BACSU Rqc2 homolog RqcH (Gene Name=rqcH)

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