Structure of PDB 7nhk Chain 0 Binding Site BS01

Receptor Information
>7nhk Chain 0 (length=495) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IELKQLSFAYDNQEALLFDQANITMDTNWKLGLIGRNGRGKTTLLRLLQK
QLDYQGEILHQVDFVYFPQTVAEEQQLTYYVLQEVTSFEQWKLERELTLL
NVDPEVLWRPFSSLSGGEKTKVLLGLLFIEENAFPLIDQPTNHLDLAGRQ
QVAEYLKKKKHGFILVSHDRAFVDEVVDHILAIEKSQLTLYQGNFSIYEE
QKKLRDAFELAENEKIKKEVNRLKETARKKAEWSMNREGDKYGNAKEKGS
GAIFDTGAIGARAARVMKRSKHIQQRAETQLAEKEKLLKDLEYIDSLSMD
YQPTHHKTLLTVEELRLGYEKNWLFAPISFSINAGEIVGITGKNGSGKSS
LIQYLLDNFSGDSEGEATLAHQLTISYVRQDYEDNQGTLSEFAEKNQLDY
TQFLNNLRKLGMERAVFTNRIEQMSMGQRKKVEVAKSLSQSAELYIWDQP
LNYLDVFNHQQLEALILSVKPAMLVIEHDAHFMKKITDKKIVLKS
Ligand information
>7nhk Chain A (length=2905) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaagugaauaagggcgcacgguggaugccuuggcacuaggagccgauga
aggacgggacuaacaccgauaugcuuuggggagcuguaaguaagcuauga
uccagagauuuccgaaugggggaacccaauaucuuuuauaggauauuacu
uuucagugaauacauagcugauuagagguagacgcagagaacugaaacau
cuuaguaccugcaggaagagaaagaaaauucgauucccugaguagcggcg
agcgaaacgggaagagcccaaaccaacaagcuuguugggguuguaggacu
ccgauaugguagucuguuaguauaguugaaggauuuggaaaauuccgcua
aagagggugaaagccccguagacgaaaugcugacaacaccuaggaggauc
cugaguacggcggaacacgagaaauuccgucggaauccgcggggaccauc
ccgcaaggcuaaauacucccuagugaccgauagugaaccaguaccgugag
ggaaaggugaaaagcaccccggaaggggagugaaauagauccugaaaccg
ugugccuacaacaagucaaagcucguuaaugagugauggcgugccuuuug
uagaaugaaccggcgaguuacgauugcaugcgagguuaagucgaagagac
ggagccgcagcgaaagcgagucugaauagggcgaaugaguauguagucgu
agacccgaaaccaugugaucuacccauguccagguugaaggugcgguaaa
acgcacuggaggaccgaacccacguacguugaaaagugcggggaugaggu
guggguagcggagaaauuccaaacgaacuuggagauagcugguucucucc
gaaauagcuuuagggcuagccucggaauugagaaugauggagguagagca
cuguuuggacuaggggcccaucucggguuaccgaauucagauaaacuccg
aaugccauucauuuauauccgggagucagacugcgagugauaagauccgu
agucgaaagggaaacagcccagaccaccagcuaaggucccaaaauauaug
uuaaguggaaaaggaugugggguugcacagacaacuaggauguuggcuua
gaagcagccaccauuuaaagagugcguaauagcucacuagucgagugacc
cugcgccgaaaauguaccggggcuaaacauauuaccgaagcuguggacua
caccauuagguguagugguaggagagcguucuaagggcguugaaggucga
ucgugaggacggcuggagcgcuuagaagugagaaugccgguaugaguagc
gaaagacaggugagaauccuguccaccguaugacuaagguuuccugggga
aggcucguccgcccaggguuagucgggaccuaagccgaggccgauaggcg
uaggcgauggacaacagguugauauuccuguaccaguuguuuuuguuuga
gcaauggagggacgcaguaggcuaaggaaugcaugcgauuggaagugcau
guccaagcaaugagucuugaguagaguuaaaugcuuuacucuuuaaggac
aaguugugacggggagcgaaauaauaguagcgaaguuccugacgucacac
ugccaagaaaagcuucuagugagaaaacaacugcccguaccguaaaccga
cacagguagucgaggagaguauccuaaggugagcgagcgaacucucguua
aggaacucggcaaaaugaccccguaacuucgggagaaggggugcugacuu
cggucagccgcagugaauaggcccaagcgacuguuuaucaaaaacacagg
ucucugcaaaaucguaagaugaaguauaggggcugacgccugcccggugc
uggaagguuaagaggauggguuagcuucggcgaagcucagaauugaagcc
ccaguaaacggcggccguaacuauaacgguccuaagguagcgaaauuccu
ugucggguaaguuccgacccgcacgaaaggcguaacgauuugggcacugu
cucaacgagagacucggugaaauuuuaguaccugugaagaugcagguuac
ccgcgacaggacggaaagaccccauggagcuuuacuguaguuugauauug
aguguuuguaccacauguacaggauagguaggagccgaugagaccggaac
gcuaguuucggaggaggcgcuggugggauacuacccuuguguuaugaacc
cucuaacccgcaccacuaaucguggugggagacagugucagaugggcagu
uugacuggggcggucgccuccuaaaagguaacggaggcgcccaaagguuc
ccucagaaugguuggaaaucauucgaagaguguaaaggcagaagggagcu
ugacugcgagaccuacaagucgagcagggacgaaagucgggcuuagugau
ccggugguuccgcauggaagggccaucgcucaacggauaaaagcuacccu
ggggauaacaggcuuaucucccccaagaguccacaucgacggggagguuu
ggcaccucgaugucggcucgucgcauccuggggcuguagucggucccaag
gguugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgu
cgugagacaguucggucccuauccgucgcgggcguuggaaauuugagagg
agcuguccuuaguacgagaggaccgggauggacuuaccgcugguguacca
guuguucugccaagggcauugcuggguagcuauguagggaagggauaaac
gcugaaagcaucuaagugugaagcccaccucaagaugagauuucccauuu
cuuuaagaaaguaagaccccugagagaugaucagguagauagguuggaag
uggaaggcuagugauaguuggagcggaccaauacuaaucggucgaggacu
uaacc
.<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<.....
.<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<<....>>>>>>>>.<<
..<<<<<.........>>>>>..>>.>>....<<<<<......<<....>
>.......>>>>.>.........<<<..>>>..<<<<<......<<....
.>>.....>>>>>..(((....<<<<<<<..>>>>>>>......<<<<<<
<<.....<<<.<<.<<<<<<<<<.<<<...<<<.<......>.>>>((..
....<<<.....))>>>...>>>...>>>>>>>>>>>>>>..>>>>..>>
>>.....<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>
>>>>..)))......]].>>>>>>>.]]...............<<....>
>....]].........<<<<....>>>>..................>>>>
>>>>>>>.......<<<<..<<<<......>>>>..>>>>...<.<....
....>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<<<.....>>>
...>>>...<<....>>..<<<<.....>>>>......>>>>>>>>>>>>
>..<<.<...<<<.<<.....<<<<<<<<<..<<<....<<<<<<.....
.>>>>>>.....>>>...<<<.<<<<<........>>>>>>>>....>>>
>>>>>>...<<<.....>>>......>>.>>>......>.>>..<<<<<<
....<<<<<....>>>>><<<<<<<<.....<<<<<<<<<.....<<<..
.<<<<<<<<...<<.<<<<.....>>>>..>>...>>>>>>>>..>>.>.
....>>>>.>>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>
>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<
<...........<<..<<<<<<<<<........<<<<<.<<...<<<...
......>>>...>>.........<<......>>...>>>>>....>>>>>
>>>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<
<<<<....>>>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.
<<....>>.>>>>>...>>.>>>>>>>..>.....>>>>>>.......<<
....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<..
.<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>.
..>>>...>>...<<<<<........>>>>>))<<<<<<<<<<<......
<<...<<<<....<<<<..<<...<<<.<.<<<<<<...(((....>>>>
>><<..<<<<<..<<<<.<<<<<<<<<.....>>>>>>>>>.....>>>>
..>>>>>...>>...<<............>>.....>>>>....>>...>
>>>.........>>>>..>>..>>>>>>>>>>>>>>>..>>.....<<..
....>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.
<<...............<<<<<...............>>>>><<<<<<..
..>>>>>>............<<<<<<<<<..<<<.........>>>..<<
<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<
<<<..<<<...<<...<<<<<..<<....>>...>>>>>...>>...>>>
>>>>>..>>>>><<<<<<.......>>>>>>........<..........
.<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>.....
>>.>>>>>>>>.>>>>>>...........<<<<<........>>>>>..<
<<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<
<<.<<<<<<<.<<<<...........<<<<<..<<<.......<<<<<<<
....>>>>>>>....>>>............>>>>>..>>>>.>>>>>>>.
>>>....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>
..<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<
<<...<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>
...<<<<..<<<......>>>..>>>>.<<<....>>>.>>)))].....
.<<<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>
>>>.......<<<<...<<<<<<...<<.......>>...>>>>>>....
>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..
>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<
<....>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<
..<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<
<<<<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<
<<<...........>>>>>...>>>>.>>>>.......>>>>>>>..<<<
<.....>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<
<.....<<<<....>>>>....>>...>>>>>.>>>...>>>>....>>>
>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7nhk Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		W32 W94 E97 R98 T101 Y194 Q195 Q204 F211 K218 R225 W236 R240 E241 K244 Y245 G246 N247 A248 K251 G252 G254 A255 I256 F257 D258 T259 G260 G263 R265 R268 M270 K271 R272 K274 H275 R279
Binding residue
(residue number reindexed from 1)		W29 W91 E94 R95 T98 Y191 Q192 Q201 F208 K215 R222 W233 R237 E238 K241 Y242 G243 N244 A245 K248 G249 G251 A252 I253 F254 D255 T256 G257 G260 R262 R265 M267 K268 R269 K271 H272 R276
Gene Ontology
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UnboundLocalError		Python 3.6.8: /usr/bin/python3
Sat Nov 16 11:37:49 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()
   1435     title=pdb2title(pdbid)
   1436     if bs.startswith("BS"):
=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)
   1438     else:
   1439         if lig3:
pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '7nhk', asym_id = '0', bs = 'BS01', title = 'Structural basis of ABCF-mediated resistance to ...gramin A antibiotics in Gram-positive pathogens. '
 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='7nhk', asym_id='0', bs='BS01', title='Structural basis of ABCF-mediated resistance to ...gramin A antibiotics in Gram-positive pathogens. ')
   1295         display_ec(ec,csaOrig,csaRenu)
   1296     if go:
=> 1297         display_go(go,uniprot,pdbid,asym_id)
   1298     return pubmed,uniprot
   1299 
global display_go = <function display_go>, go = '0005524,0016887', uniprot = '', pdbid = '7nhk', asym_id = '0'
 /var/www/html/BioLiP/pdb.cgi in display_go(go='0005524,0016887', uniprot='', pdbid='7nhk', asym_id='0')
    480         '''.replace("$namespace_link",namespace_link
    481           ).replace("$namespace",namespace
=>  482           ).replace("$uniprot",u
    483         ))
    484         for l,(term,name) in enumerate(go2aspect[Aspect]):
u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>