Structure of PDB 7m4v Chain 0 Binding Site BS01

Receptor Information
>7m4v Chain 0 (length=51) Species: 480119 (Acinetobacter baumannii AB0057) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRDKIRLVSSAGTGYFYTTTKNKRTMPEKMEIKKFDPKIRQHVIFKEAKI
K
Ligand information
>7m4v Chain A (length=2732) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agucaaguaauuaagugcaugugguggaugccuuggcagucagaggcgau
gaaagacgugauagccugcgaaaagcuccggggaggcggcaaauauccuu
ugauccggagaugucugaaugggggaacccaccuacuuuaagguagguau
ugcaacaugaauacauaguguugcaaggcgaacgaggggaagugaaacau
cucaguacccuuaggaaaagaaaucaauugagauucccucaguagcggcg
agcgaacggggaucagcccauuaaguuauguguguuuuaguggaacgcuc
ugggaagugcgaacguagagggugauauucccguacacgaaagggcacac
auaaugaugacgaguagggcgaggcacgugaaaccuugucugaauauggg
gggaccauccuccaaggcuaaauacuccugacugaccgauagugaaccag
uaccgugagggaaaggcgaaaagaaccccugugaggggagugaaauagau
ccugaaaccgcaugcauacaagcagugggagcaccuucguggugugacug
cguaccuuuuguauaaugggucagcgacuuauauucaguagcgagguuaa
ccguauaggggagccguagagaaaucgagucuuaauagggcguuuaguug
cuggguauagacccgaaaccaggcgaucuauccaugagcagguugaaggu
uggguaacacuaacuggaggaccgaacccacugucguugaaaagccaggg
gaugacuuguggauaggggugaaaggcuaaucaagccuggugauagcugg
uucuccccgaaagcuauuuagguagcgccucggacgaauaccauaggggg
uagagcacuguuucggcaccgaugcaaacuccgaauaccuaugaguacua
uccgggagacagacugcgggugcuaacguccguagucaagaggaaaacaa
uccagaccgccagcuaaggccccaaaaucauaguuaagugggaaacgaug
ugggaaggcauagacagcuauagucgagucggccugcgcggaagauguaa
cggggcuaaaacuaugugccgaagcugcggauguauacuuuguauacgug
guaggggagcguucuguaagccgaugaagguguguugagaagcaugcugg
agguaucagaagugcgaaugcugacgugaguaacgacaaaacgggugaaa
aacccguucgccgaaagaccaaggguuccaguccaacguuaaucggggcu
gggugagucgaccccuaaggcgaggccgaaaggcguagucgaugggaaaa
ugguuaauauuccauuacuucuguguaaugcgaugagaggacggagaagg
cuaaaucagccuggcguugguuguccaggugaaaggauguaggcauguau
cuuaggcaaauccgggguacucuaugcugagaucugauagcaagcuguac
uugugcagcgaagugguugaugccaugcuuccaggaaaagucucuaagcu
ucaguuacacaggaaucguacccgaaaccgacacagguggucaggucgag
uagaccaaggcgcuugagagaacucugcugaaggaacuaggcaaaauggu
accguaacuucgggagaagguacgcuguuguuggugauggaacucgcuuc
cugagcugacgacagccgcagaaaccaggccgcugcaacuguuuauuaaa
aacauagcacucugcaaacacgaaaguggacguauagggugugaugccug
cccggugcuggaagguuaauugaugggguuagcguaagcgaagcucuuga
ucgaagccccaguaaacggcggccguaacuauaacgguccuaagguagcg
aaauuccuugucggguaaguuccgaccugcacgaauggcauaaugauggc
ggcgcugucuccagcagaggcucagugaaaucgaaaucgcugugaagaug
caguguacccgcggcuagacggaaagaccccgugaaccuuuacugcagcu
ugacacugaacuuugauugagguucuaacucugucccgugauccgggacg
aggaccgugucugguggguaguuugacuggggcggucuccuccuaaagag
uaacggaggaguacgaaggugcgcucagcguggucggaaaucacgcguag
aguauaaaggcaaaagcgcgcuuaacugcgagacccacaagucgagcagg
uacgaaaguaggucuuagugauccggugguucuguauggaagggccaucg
cucaacggauaaaagguacucuggggauaacaggcugauaccgcccaaga
guucauaucgacggcgguguuuggcaccucgaugucggcucaucucaucc
uggggcugaagcaggucccaaggguauggcuguucgccauuuaaagaggu
acgcgagcuggguuuagaacgucgugagacaguucggucccuaucuaccg
ugggcgcuggaaauuugagaggaucugcuccuaguacgagaggaccagag
uggacgaaccucugguguaccgguugugacgccagucgcaucgccgggua
gcuauguucggaagggauaaccgcugaaagcaucuaagcgggaagccuac
cucaagauaagauuucccuaggacuuuauguccucuaaagagccguucga
gacuaggacguugauagguuggauguggaagcauagugauaugugaagcu
gaccaauacuaauugcucgugaggcuugacua
<<<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<...
...<<<<<<.[..(((.>>>.....<<<<<<<..<<.)))...]..>>..
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<<....>>...<<<<<.....<<....
.>>....>>>>>...<<<...<..<<<<<<<<<<<<<<.<<<...<<<.<
......>.>>>((......<<<.....))>>>...>>>...>>>>>>>>>
>>>>>...>.......<<<<<<<<.........>>>>>>>>......<<<
<<..<<<<>>>>>..>>>......]].>>>>>>>.]].............
..<<....>>....]].........<<<<.....>>>>............
......>>>>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>
>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...
<<.....>>...>>>...<<....>>..<<<<.....>>>>.....>>>>
>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<
<<<......>>>>>>.....>>>...<<<.<<<.<........>.>>>>>
>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>.>>
..<<<<<<....<<<<<....>>>>>.<<<<<<<....<<<<<<<<<...
..<<<...<<<.<<<<..>>>>.>>>..>>.>.....>>>>>>.>>>...
>>>>>>.>...<<<<<<<<<<......>>>>>>>>>>....<<<......
>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<
<<<<..<<........<<<..>>>....>>..>>>>>.>>..........
.)))......>>>>>>.>>>...>>>>>>><<<<<<<<...>>>>>>>>.
...>>>>>><.<<<<<...<<<......<<<<<<<<....>>>>>>>>..
.>>>..>>>>>..>.....>>>>>><......<<.....<<<<<<.....
..>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>
>>....((<<<.<<<...<<<...<<<....>>>...>>>...>>>..<<
<<<........>>>>>))<<<<<<<<<<<<<...<<<<....<<<<..<<
<..<<<<<<<<<<<...((((...>>>>>>....<<<<...<<<<.<<<<
<<..<<.....>>.>>>>>>....>>>>...>>>>........<<<<<..
....>>>>>....>>>>>...>>>...>>>>.........>>>>...>>.
...>>>>>>>>>>>.>>>..>>.....<<......>>>>>>>.<<<<...
..>>>>..>>>>..<<<<....<<<<<<<<.<<...............<<
<<<.....<..>......>>>>><<<<<<<<<<<<...<<<<.....>>>
>...>>>>>>>>>>>>............<<<<<<<<<..<<<........
.>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<
<<..<<<<<<<..<<<<.......<<<<<<.<<....>>..>>>>>>...
....>>>>>>>>>..>>>>><<<<<<.......>>>>>>........<..
.........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>
>>>.....>>.>>>>>>>>.>>>>>>.....>.....<<<<<........
>>>>>..<<<<<<<.<<<<.[[......<<<<.[[<<<<..<<<<..<<<
.<<<<<.<<<<<<<<..>>>>>>>>...<<<.<<<<<<.....>>>>>>>
>>....>>>>>.>>>...>>>>..<<<<.....>>>><<<<<<.......
....>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>....
.<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>>>>.
<<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>>>>>
.............>>>>..]]>>>>.......<<<<...<<<<<<...<<
.......>>...>>>>>>....>>>.>.......<<<<<.<<<<<<..<<
<<<<<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>>>>>
..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..>>>>>>>
>>>>....<<<<<<<...<<<<..<<<<<<.................>>>
>>>.<<<<<...<<<<...<<<<<<<<<<<))))>>>>>>..>>>>>...
>>>>.>>>>>...<<<....<<<<<...........>>>>>....>>>.>
>>>.......>>>>>>>..<<<<<.....>>>>><....<<<<<<<<<..
.....>>>>>....<<<<<<<<..<<....<<<<<....>>>>>...>>.
..>>>>>.>>>...>>>>..>..>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB7m4v Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii.
Resolution2.54 Å
Binding residue
(original residue number in PDB)
R2 K4 F16 N22 M26 M30 I32 K33 F35 P37 R40 H42
Binding residue
(residue number reindexed from 1)
R2 K4 F16 N22 M26 M30 I32 K33 F35 P37 R40 H42
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7m4v, PDBe:7m4v, PDBj:7m4v
PDBsum7m4v
PubMed34044590
UniProtA0A7U4DFF9

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