Structure of PDB 7dvq Chain 0 Binding Site BS01

Receptor Information
>7dvq Chain 0 (length=100) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VCEKCEKKLGTVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYG
KNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7dvq Chain 0 Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7dvq Structure of the activated human minor spliceosome.
Resolution2.89 Å
Binding residue
(original residue number in PDB)		C3 C6 C83 C86
Binding residue
(residue number reindexed from 1)		C2 C5 C82 C85
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0030165 PDZ domain binding
GO:0044877 protein-containing complex binding
GO:0097110 scaffold protein binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0031122 cytoplasmic microtubule organization
GO:0035372 protein localization to microtubule
GO:0045184 establishment of protein localization
GO:0099151 regulation of postsynaptic density assembly
GO:1902897 regulation of postsynaptic density protein 95 clustering
Cellular Component
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0014069 postsynaptic density
GO:0030425 dendrite
GO:0042995 cell projection
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0043198 dendritic shaft
GO:0045202 synapse
GO:0098978 glutamatergic synapse
GO:0099092 postsynaptic density, intracellular component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7dvq, PDBe:7dvq, PDBj:7dvq
PDBsum7dvq
PubMed33509932
UniProtQ9P021|CRIPT_HUMAN Cysteine-rich PDZ-binding protein (Gene Name=CRIPT)

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