Structure of PDB 6nu3 Chain 0 Binding Site BS01

Receptor Information
>6nu3 Chain 0 (length=108) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAPKNRRTIEVNRCRRRNPQKLIKVKNNIDVCPECGHLKQKHVLCAYCYE
KVCKETAEIRRQIGKQEGGPFKAPTIETVVLYTGETPSEQDQGKRIIERD
RKRPSWFT
Ligand information
>6nu3 Chain A (length=1472) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagcaaccuuagcc
aaaccauuuacauaaaguauaggcgauagaaauuguggcgcaauagauau
aguaccgcaagggaaagaugaaaaauuauaaccaagcauaauauagcaag
gacuaaccccuauaccuucugcauaaugaauuaacuagaaauaacuuugc
aaggagagccaaagcuaagacccccgaaaccagacgagcuaccuaagaac
agcuaagagcacacccgucuauguagcaaaauagugggaagauuuauagg
uagaggcgacaaaccuaccgagccuggugauagcugguuguccaagauag
aaucuuaguucaacuuuaaauuugcccacagaaccaaauccccuuguaaa
uuuaacuguuaguccaaagaggaacagcucuuuggacacuaggaaaaaac
cuuguagagagaguaaaaaauuuaacacccauaguaggccuaaaagcagc
caccaauuaagaaagcguucaagcucaacaccaaaaaucccaaacauaua
acugaacuccucacacccaauuggaccaaucuaucacccuauagaagaac
uaauguuaguauaaguaacaugaaaacauucuccuccgcauaagccugcg
ucagaucacacugacaauuaacagcccaauaucuacaaucaaccaacaag
ucauuauuacccucacugucaacccaacacaggcaugcucauaaggaaag
guuaaaaaaaguaaaaggaacucggcaaaucuuaccccgccuguuuacca
aaaacaucaccucuagcaucaccaguauuagaggcaccgccugcccagug
acacauguuuaacggccgcgguuaaccgugcaaagguagcauaaucacuu
guuccuuaaauagggaccuguaugaauggcuccacgaggguucagcuguc
ucuuacuuuuaaccagugaaauugaccugcccgugaagaggcgggcauaa
cacagcaagacgagaagacccuauggagcuuuaauuuauuaaugcaaaca
guaaccugcauuaaaaauuucgguuggggcgaccucggagcagaacccaa
ccuccgagcaguacaugcuaagacuucaccagucaaagcgaaccucaauu
gauccaauaacuugaccaacggaacaaguuacccuagggauaacagcgca
auccuauucuagaguccauaucaacaauaggguuuacgaccucgauguug
gaucaggacaucccgauggugcagccgcuauuaaagguucguuuguucaa
cgauuaaaguccuacgugaucugaguucagaccggaguaauccaggucgg
uuucuaucuacuuuauuccucccuguacgaaaggacaagagaaauaaggc
cuacuucacaaagcgccuucccccguaaaugauaucaucucaacuuagau
acccacacccaagaacaggguu
<<<.......<<<<....................................
<<....>>.....<.....<<.....>>....>...>>.>>.........
....<<....>>......................>>>...........<<
<.......>>>...<............>.<<<<<<.........<<<.<<
..<<....>>...>>.>>>...<<.<..<<<<<.<.....<<<<<.<<<.
.<<<...>>>...<<<..<<<<........>>>>.>>>....>>>.>>>>
>...<<.......>>......>.>>>>...>..>.>>..<<<<<<....<
<<<....>>>>.<<.<<<<<<<.<<.....<<......>>.....>>.>>
>>>>>..>>..<<<<<<<<<<......>>>>>>>>>>.<.<<<......>
>>.>..<<<.<<<...<..............<....<<<.........>>
>....>.......<<<......>>>.........................
..>...>>>>>>........>>>>>>...<<<<<......>>>>>.....
....>>>>>><......<<..<<<....>>><<<...<<<<........<
<<<<......>>>>>......<<<...<<<<...................
....>>>>.......>>>.....<<......>>.>>>>......>>>..<
<<<...<<<<<<<<.<<................<<<<<<..<<<......
...>>>...<<<<<<.............>>>>>>....<<<.<<<..<<<
<<....>>>..>>>>><<<<<....>>>>>........<...........
<<<<<<.....>>>>>>.....>....>>>....>>.>>>>........>
>.>>>>>>>>>>>>.>>.....>.....<<<<<........>>>>>....
...<<..<<<.<<......<<<<.<<<<<...<<<<<.<<<<<<<<....
......>>>>>>>>>>>>>..<<<<.....>>>><<<<<<..........
.>>>>>>..<<.....<<<..<<<<.....>>>>..>>>....>>.....
....<<<....>>>.............>>>..>>>>>>.......<<<..
<<<<<<<<...<<.......>>...>>>>>>>..>.>>.>.......<.<
<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>
>>>.....>>>>>..>...>>>..>....<<<<<<<....>>>.>>>>..
..>>..>>>.>>..<<<.<<<.................>>>.>>><<<<<
...<<<....>>>.>>>>>......<<<................>>>...
......<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6nu3 Structural insights into unique features of the human mitochondrial ribosome recycling.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		A79 A80 P81 K82 N83 R84 R85 T86 I87 V89 R91 C92 R93 R95 N96 Q98 N106 H120 A135 R138 R139 F149
Binding residue
(residue number reindexed from 1)		A1 A2 P3 K4 N5 R6 R7 T8 I9 V11 R13 C14 R15 R17 N18 Q20 N28 H42 A57 R60 R61 F71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6nu3, PDBe:6nu3, PDBj:6nu3
PDBsum6nu3
PubMed30962385
UniProtQ9BYC8|RM32_HUMAN Large ribosomal subunit protein bL32m (Gene Name=MRPL32)

[Back to BioLiP]